Does Cordyceps Relieve Anxiety? - HONE
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Does Cordyceps Relieve Anxiety?

  • 17 min read

Does Cordyceps Relieve Anxiety? - HONE

Feeling stressed and anxious? Cordyceps mushrooms may offer natural relief. This fungal powerhouse can calm nerves, ease worry, and help you adapt to life’s daily stressors. 

Article jumplinks:

What is anxiety?

What is Cordyceps militaris?

Does cordyceps ease anxiety?

Is cordyceps adaptogenic?

Cordyceps and neurotransmitters

Can cordyceps lower neuroinflammation?

How much cordyceps should I take?

Are there side effects from cordyceps?

How to reduce anxiety with cordyceps

While more research is still needed, several studies suggest cordyceps supplementation can reduce anxiety symptoms and help people feel more relaxed and focused. Their adaptogenic properties certainly help balance the nervous system for improved resilience.

If you’re looking to soothe anxiety without prescription medications, sipping our cordyceps tea blended with relaxing matcha is an excellent way to start your day. The result is a nourishing beverage that eases worries and leaves you feeling zen from head to toe.

Mushroom Matcha Box - 10 Compostable Packets

We’ve already explored the effects of Cordyceps militaris on depression. Now, let us explore the health benefits of cordyceps for alleviating stress and anxiety. 

What Is Anxiety?

Anxiety is a normal human emotion that involves feelings of worry, unease, or fear. It's perfectly natural to feel stressed or anxious in certain situations, like when facing a challenge at work or making a big decision. A small amount of anxiety can even be beneficial—it makes us more alert to potential threats and focuses our attention on the task at hand.

However, when feelings of worry or fear become persistent and excessive, they may disrupt our daily lives and become what is known as an anxiety disorder. They make it very difficult to control our emotional responses and make us overreact to minor triggers. 

According to the Cleveland Clinic, anxiety disorders are the most common mental illnesses in the US, affecting nearly 40 million Americans and over 200 million people worldwide. 

Under this umbrella term, there are several types of anxiety, all characterized by constant feelings of worry and dread. 

  • Generalized anxiety disorders
  • Social anxiety
  • Separation anxiety
  • Panic disorder
  • Selective mutism
  • Phobias
  • Substance- or medication-induced anxiety

What Symptoms Does a Person With Anxiety Show?

Anxiety often involves a combination of mental, physical, behavioral, and emotional symptoms. They can look different for each person and tend to vary based on the specific anxiety disorder. 

Some of the most common symptoms across the different types of anxiety include:

  • Excessive worry and dread
  • Obsessive thoughts
  • Intrusive thoughts
  • Feeling tense or on edge (often involving panic attacks)
  • Difficulty concentrating
  • Nervous habits (e.g., restlessness, fidgeting, and nail biting)
  • Irritability and impatience
  • Feeling overwhelmed 
  • Headaches 
  • Muscle tension
  • Problems with the gastrointestinal tract
  • Chronic fatigue
  • Insomnia

Anxiety disorders can also contribute to the development or worsening of other mental and physical health conditions, leading to a wider spectrum of symptoms. 

  1. Depression 
  2. Substance abuse
  3. Digestive or bowel problems
  4. Chronic pain
  5. Social isolation
  6. Problems functioning at school or work
  7. Poor quality of life
  8. Suicide

What Causes Anxiety?

The causes of clinical anxiety are complex, involving a combination of genetic, environmental, brain chemistry, and personality factors. These are some of the factors that may trigger or perpetuate excessive anxiety: 

  1. Trauma
  2. Chronic stress
  3. Medical conditions 
  4. Chronic inflammation 
  5. Imbalances in neurotransmitters
  6. Negative thought patterns (rumination and catastrophizing)

How Is Anxiety Treated?

Anxiety is highly treatable. There are strategies and treatment options available to help you overcome anxiety struggles. 

  1. Psychotherapy (cognitive behavioral therapy and exposure therapy): the goal is to change negative thought/behavior patterns and desensitize triggers.
  2. Medication: antidepressants like selective serotonin reuptake inhibitors (SSRIs) and  serotonin and norepinephrine reuptake inhibitors (SNRIs) (Effexor, Cymbalta) can help regulate brain chemistry.
  3. Complementary approaches: exercise, meditation, yoga, and mindfulness practices help counter the physical tension.
  4. Stress management: learning to set priorities can help reduce anxiety-provoking stress.
  5. Lifestyle changes: limiting alcohol, improving sleep habits, and quitting smoking can also lessen the severity of anxiety for some people.
  6. Integrative approach: involves a combination of therapy, medications as needed, lifestyle changes, stress management, and relaxation techniques.

Conventional treatments can provide validated relief options for many. However, some individuals are seeking more holistic approaches to anxiety management. This has sparked growing interest in the therapeutic potential of natural medicinal mushrooms to alleviate anxiety and instill calm. 

One such super-mushroom is Cordyceps militaris. Cordyceps has been shown to influence anxiety pathways through reducing inflammation, optimizing neurotransmitter balance, and strengthening the nervous system's resilience against stressors—and is a completely natural alternative to prescription medication (which, by the way, comes with a plethora of unpleasant side effects). 

With cordyceps, the only side effect you’ll experience is the delightful earthy flavor that makes our cordyceps matcha tea pop. This expertly crafted mushroom blend highlights cordyceps' rich taste, amplified by the fresh grassy notes of premium matcha

 Mushroom Matcha - 30 Serving Jar

The health perks of our mushroom matcha tea will leave you feeling balanced, relaxed, and ready to take on anything life throws your way. 

What Is Cordyceps Militaris?

Cordyceps militaris is one of the two most common species in the Cordyceps fungus genus. C. militaris is grown commercially in labs and is more available and cheaper than C. sinensis. Both have been used in traditional Chinese medicine due to their extraordinary health benefits. 

Read our in-depth guide on the exact differences between C. militaris and C. sinensis for more information on these two superfood fungi. 

Many studies, including the 2014 review article, discovered that cordyceps mushrooms have “anti-bacterial, anti-fungal, larvicidal, anti-inflammatory, anti-diabetic, anti-oxidant, anti-tumor, pro-sexual, apoptotic, immunomodulatory, anti-HIV and many more activities.” 

Bioactive compounds like cordycepin, adenosine, polysaccharides, and many others make up the rich chemical composition of these functional mushrooms and allow for a variety of health benefits. 

Here’s a glimpse into the extraordinary health benefits of Cordyceps militaris:

  1. Boost energy and improve athletic performance and endurance
  2. Improve brain health
  3. Improve sleep
  4. Improve gut health and regulate the gut flora
  5. Improve sexual function in men and women by increasing libido
  6. Boost testosterone levels, which helps maintain healthy reproductive system in men (read more about the benefits of cordyceps on fertility)
  7. Promote heart health
  8. Fight cancer

To amplify its potent medicinal and therapeutic properties, we paired cordyceps with the highest quality ceremonial grade matcha. That means you get the most rich, smooth, and nutritious cup of tea to revitalize your mind and body.

Before jumping into the anxiety-busting properties of cordyceps mushrooms, here’s something about all the reasons to add matcha to your next shopping list.

Or just order a jar of our amazing matcha tea with cordyceps. It saves you time and energy and doubles down on the health benefits.

How Does Cordyceps Lower Anxiety?

There’s a reason why cordyceps mushrooms are the most popular in traditional Chinese medicine:their anxiolytic properties can be used to lower stress and anxiety, prevent depression, reduce inflammation, and influence neurotransmitters that regulate mood and emotions. 

A 2020 animal study showed that cordyceps supplementation improved behavioral deficiencies caused by unpredictable chronic mild stress (UCMS) and lowered anxiety levels. 

Unpredictable chronic mild stress is an experimental model used in rodent studies to induce depression-like and anxiety-like behaviors. Researchers expose the animals to different mild physical and psychological stressors in an unpredictable pattern to investigate their behavioral changes that mimic some symptoms of depression and anxiety disorders in humans. 

In the 2020 study, researchers looked at whether an extract formula combining Poria cocos, another fungus, and Cordyceps militaris could help treat depression and anxiety in an animal model. 

This fungus combo may have antidepressive and anxiolytic effects. The extract formula had a positive effect on key neurotransmitters related to mood, motivation, and brain activity in ways that could ease depressive and anxious symptoms. Also, cordyceps reduced inflammation markers and protein expression related to inflammation. 

Want to try cordyceps for anxiety? Our mushroom matcha tea is just the thing. Aside from the powerful cordyceps, this blend contains matcha, which is one of the best-known natural sources of L-theanine

L-theanine is an amino acid that can help you induce a calm state of alertness and focus. It works beautifully with cordyceps and other matcha compounds to promote relaxation and create a sense of tranquility. 

Read more about the zen-like effects of L-theanine

 Mushroom Matcha Box - 10 Compostable Packets

So how does cordyceps relieve anxiety? Let’s investigate its adaptogenic, anti-inflammatory, and neurotransmitter-regulating properties to find out. 

Adaptogenic Properties of Cordyceps

Cordyceps mushrooms are adaptogenic. They help your body become more resilient and equipped to handle all sorts of stress. Whether it's physical, mental, or emotional stress, cordyceps supports your central nervous system in coping with it.

According to a 2018 study, adaptogens “can prevent and resist stress because these substances can activate the secretion of cortisol… allowing the body to adapt.” They modulate the body's stress response through the hypothalamic-pituitary-adrenal (HPA) axis.

The HPA axis is a complex network involving the hypothalamus, pituitary gland, and adrenal glands. These are essential components of the endocrine system, which is responsible for regulating important bodily functions through the secretion of hormones.

  • The hypothalamus regulates physiological functions such as body temperature, hunger, and thirst. 
  • The pituitary gland, often referred to as the "master gland," secretes hormones that control other endocrine glands and influence growth, reproduction, and stress responses. 
  • The adrenal glands produce hormones such as cortisol and adrenaline, playing a key role in the body's stress response, metabolism, and blood pressure regulation.

As you can see, they are all important factors in reducing stress and anxiety. Adaptogens like cordyceps help regulate cortisol levels, leading to reduced anxiety and stress. 

Find out more about how adaptogens work.

The Beneficial Effects of Cordyceps on Cortisol

Cortisol, often called the "stress hormone," is produced in the adrenal glands. It helps control our body's response to stress and regulates energy, metabolism, and the immune system. While it's important for short-term stress reactions, chronically elevated cortisol levels are associated with anxiety and mood disorders. 

2015 study on the antifatigue effects of cordyceps revealed its beneficial effects on the stress hormone. While the study focused on fatigue, some of the mechanisms involved, such as antioxidant effects, hormone regulation, and energy balance, could also potentially have implications for stress and cortisol levels. 

The study found that Cordyceps militaris treatment at different doses led to significant increases in serum cortisol levels in both female and male mice after swimming exercise. Cordyceps may influence cortisol production in response to exercise, potentially affecting the body's stress response

Another study on chronic, mild stress-induced mice revealed that an important bioactive compound from cordyceps, called cordycepin, could help with depression-like behaviors caused by chronic stress. The results showed that cordycepin could influence the levels of neurotransmitters like serotonin and dopamine, exerting antidepressant-like effects on stress in an animal model.

[Cordycepin] remarkably improved depression-like behavior in [chronic unpredictable mild stress] mice and its antidepressant activity is mediated, at least in part, by the upregulating BDNF and downregulating 5-HT2AR levels and inflammation in hippocampus.

In other words, cordycepin increased brain-derived neurotrophic factor (BNDF) protein expression, reduced the mood-affecting receptor 5-HT2AR, and soothed inflammation in the animals’ brains. BDNF plays a crucial role in promoting the growth, development, and maintenance of nerve cells. By increasing it, cordyceps mushrooms support healthy neuronal connections and signaling associated with mood regulation and even pave the way for hippocampal neurogenesis. 

So cordyceps is great for mental and brain health. Who would have known? We did! That’s why we put it in our tea blend with matcha

Matcha is another natural brain-booster. This finely ground green tea powder delivers a mega-dose of L-theanine, an amino acid that works like a chill pill for the brain. Just like cordyceps, L-theanine calms nerves and takes the edge off anxiety without making you drowsy.

Mushroom Matcha - 30 Serving Jar

How Does Cordyceps Influence Neurotransmitters?

Cordyceps could impact neurotransmitter activity and contribute to reducing anxiety. Neurotransmitters are chemical messengers that regulate many aspects of mood, cognition, and mental health. 

Out of all mood-regulating neurotransmitters, serotonin and dopamine might be the most important for relieving anxiety. Here's why:

  • Serotonin influences mood, emotions, sleep, and appetite. Low serotonin is linked to anxiety and depression. 
  • Dopamine regulates motivation, pleasure, focus, and cognitive functions. Low levels of dopamine increase anxiety and diminish feelings of motivation and pleasure while lowering focus.
  • Dopamine also modulate brain pathways that control fear and worry
  • Optimal serotonin levels reduce obsessive thoughts, calm emotions, and improve sleep quality. 
  • Sufficient levels of dopamine are associated with emotional resilience. 
  • Dopamine upregulates the production of neurotrophic factors (remember BDNF?) that support neuron health and development. Enough dopamine in the brain stimulates neural stem cell proliferation and differentiation. 

Research suggests that cordyceps can increase levels of serotonin and dopamine. Higher serotonin transmission may contribute to emotional stability and a relaxed mood, while optimal levels of dopamine can enhance motivation, pleasure, and focus. By optimizing both mood-boosting neurotransmitters, cordyceps may provide elevated energy and positivity to counteract anxiety.

Cordyceps Increases Serotonin

Cordyceps mushrooms mycelia and fruiting bodies are naturally rich in tryptophan, an amino acid precursor to serotonin. Since it contains abundant tryptophan, cordyceps provides the raw material for the body to synthesize more serotonin. Increasing serotonin levels through tryptophan supplementation can help stabilize moods and relieve anxiety symptoms.

The medium overgrown with mycelium has been shown to be rich in 5-hydroxy-L-tryptophan, serotonin, and ergosterol. Pintathong et al. also determined the content of tryptophan in solid-based residues remaining after the harvest of fruiting bodies of C. militaris. (Jedrejko, et. al.)

One study examined the positive effects of Cordyceps militaris water extract (WCM) on rats with unpredictable chronic mild stress. Cordyceps reduced the turnover rate of serotonin and dopamine. This means that it helped break down both neurotransmitters more slowly, so they remained in the brain for a longer amount of time. This slower turnover rate led to their elevated levels in the brain, further reducing symptoms of anxiety and depression. 

The WCM has antidepressant-like effects, which may result from the regulation of the stress-related ROCK2/PTEN/Akt pathway. Therefore, the WCM may be developed and used for the complementary treatment of depression. (Lin, et. al.)

The effects of water extract of C. militaris also prevented anhedonia (depressive-like behavior) in rats at all doses tested. 

Adenosine-Rich Cordyceps for Elevated Levels of Dopamine

One research article suggests that cordyceps can increase dopamine levels through one of its most powerful bioactive compounds, adenosine. By blocking A2AR receptors, adenosine enhances dopamine-related effects and improves the symptoms of not only anxiety and depressive disorders but also neurological conditions like Parkinson’s and schizophrenia. 

Low dopamine levels are implicated in neurodegenerative diseases like Parkinson's disease. The loss of dopamine-producing neurons often causes motor deficits and depression, so by naturally enhancing dopamine levels, cordyceps may improve motivation, concentration, and reward-seeking behaviors while boosting brain function. 

Parkinson’s disease (PD) is a common age-related degenerative disease owing to the progressive loss of dopaminergic (DA) neurons in the substantia nigra (SN). Oxidative stress, mitochondrial dysfunction, endoplasmic reticulum stress and neuroinflammation have been documented to be responsible for the initiation and development of PD. (Sun, et. al.)

Optimizing dopamine may underlie the benefits of cordyceps mushrooms for anxiety, depression, and neurological conditions like Parkinson's that involve dopamine deficiency.

While more clinical research is needed, there is evidence that cordyceps may recalibrate brain chemistry for clear and calm mental states. Neurotransmitter modulation may be one of the key bioactive mechanisms of cordyceps for anxiety relief. 

Another mechanism is kicking inflammation to the curb.

Cordyceps Lowers Anxiety-Inducing Inflammation

Chronic inflammation in the brain has been linked to anxiety and other mood disorders. When our body detects a threat, like an infection or injury, it responds by triggering inflammation. When inflammation becomes chronic or excessive, it can affect our brain and mood. 

However, there seems to be a bidirectional relationship between inflammation and anxiety. Cordyceps has both anti-inflammatory and anxiolytic properties that may play a role in reducing both. 

Inflammation Triggers Anxiety

Chronic inflammation in the body and brain caused by infections or autoimmune diseases can trigger anxiety symptoms. Inflammatory cytokines like IL-6 and TNF-alpha alter neurotransmitter balance, neuroplasticity, and neural circuitry functioning, disrupting mood regulation. 

High levels of inflammation can disrupt the balance of neurotransmitters such as serotonin and dopamine, which play key roles in regulating our emotions. This imbalance can contribute to the development of anxiety symptoms. 

Anxiety Triggers Inflammation

Anxiety and stress can also influence our body's inflammatory response. When we feel anxious or stressed, our body releases stress hormones like cortisol. While these hormones are helpful in short bursts, chronic anxiety can lead to an overproduction of stress hormones. Excess stress hormones can promote inflammation in the body. 

Anxiety can also impact behaviors and habits that contribute to inflammation, such as poor sleep, unhealthy eating, and a lack of exercise. These factors can further fuel inflammation and create a cycle where anxiety triggers inflammation, which in turn worsens anxiety.

Cordyceps Can Lower Inflammation and Reduce Anxiety

While inflammation and anxiety reinforce each other in a self-perpetuating cycle, anti-inflammatory supplements like cordyceps may help intervene and break this connection. 

Cordycepin is one of the main molecules in cordyceps that helps reduce inflammation. A 2020 study review revealed that cordycepin-rich ethanol extracts can block inflammatory mechanisms in chronic inflammatory disorders. 

…cordycepin exerts protective effects against inflammatory injury for many diseases including acute lung injury (ALI), asthma, rheumatoid arthritis, Parkinson's disease (PD), hepatitis, atherosclerosis, and atopic dermatitis. 

Cordyceps is also rich in polysaccharides, complex biomolecules that act as crucial sources of energy. A 2014 human cell study investigated the anti-inflammatory potential of polysaccharides from Cordyceps militaris. The results showed that these molecules suppress certain types of pro-inflammatory cytokines. Reduced levels of cytokines and inhibition of their function lead to lower inflammation in the body. 

Cordyceps may help regulate the production of certain cytokines, thereby reducing the overall inflammatory response in the body. By curbing excessive inflammation, Cordyceps might indirectly contribute to a reduction in anxiety.

Chronic inflammation can wreak havoc on our health, but nature provides some powerful tools to fight back. Just like cordyceps, matcha green tea contains potent anti-inflammatory compounds to cool inflammation and restore calm. 

Just one cup of our mushroom matcha tea offers a daily dose of natural anti-inflammatories to protect your brain, lift your mood, and support your overall wellbeing. 

 Mushroom Matcha Box - 10 Compostable Packets

How Much Cordyceps Should I Take?

If using cordyceps in its whole mushroom form, a good starting dosage is 1–3 grams per day. For concentrated cordyceps extracts, the recommended dosage typically ranges from 0.5–1 gram daily.

Research studies conducted on humans have safely used between 1 and 3 grams of cordyceps per day without notable side effects. The ideal cordyceps dosage depends on your health goals and personal tolerances. 

When using cordyceps for anxiety relief, start with lower dosages of around 1 gram per day and see how you feel after a week or so. Give your body time to adapt and find the minimum effective dose that provides you with anxiety relief without side effects. 

Each of our 10-serving tea packets contains 3.5 grams of organic cordyceps and premium matcha to help you overcome stress and anxiety. You can prepare and drink it all at once (some people like their tea strong), or you can divide it into two or even three delicious cups of matcha mushroom tea.

No matter how you divide it, you'll get an optimal daily amount of organic cordyceps mushrooms every time. Follow the preparation instructions on the packet for smooth, flavorful, anxiety-busting tea.

Mushroom Matcha Box - 10 Compostable Packets

Side Effects of Cordyceps Mushrooms

Cordyceps mushrooms are considered completely safe to use when consumed responsibly. If you have allergies to yeast, mold, or other types of fungi, cross-reactivity is possible: you may be allergic to cordyceps, too.

Some rare, minor side effects like nausea, diarrhea, or dry mouth have been reported in some users. You can easily avoid these if you maintain your cordyceps intake within recommended dosing guidelines. Start with lower amounts (1–3 grams per day) and gradually increase the dosage as your body adapts to the awesome effects of cordyceps. 

Whether it’s your first time or you’re already an avid mushroom enthusiast, moderation is the key. As with any new supplement, consulting your healthcare provider is wise if you have any medical conditions or concerns.

Choose the Best Cordyceps Supplement for Anxiety

There are many ways you can include cordyceps in your diet to calm the mind. Many enjoy taking cordyceps capsules or tablets as a quick and easy fix. Others add raw or dried mushrooms to their meals, which is a far more delicious option. 

Our favorite way to take cordyceps is with our mushroom matcha tea. Just add some frothed milk to our pre-portioned tea packets and enjoy. 

With options tailored for home or on-the-go enjoyment, our invigorating mushroom blend makes it easier than ever to reap the daily benefits of cordyceps. One cup is all it takes to feel the stress-relieving difference.

To last you a full month of enjoyment, grab a jar of our cordyceps matcha tea and experience the effects for yourself. 

Mushroom Matcha - 30 Serving Jar

Cordyceps FAQ

Is cordyceps calming?

Cordyceps' potential calming effects may be related to its adaptogenic properties, which aim to help the body adapt to stressors. Its influence on the stress response could contribute to overall well-being and potentially alleviate feelings of anxiety. Some users have reported improved moods and reduced stress levels after consuming cordyceps mushroom extract. Each person’s response to adaptogenic mushrooms like cordyceps is different, so make sure to start with a low amount if you’re taking cordyceps for the first time. 

Which mushroom is best for anxiety?

According to research, the best mushrooms for anxiety are cordyceps, reishi, lion’s mane, and chaga mushrooms. 

  • Cordyceps is a rare mushroom with powerful adaptogenic properties that help regulate neurotransmitters, hormones, and immune responses. Research shows cordyceps can increase dopamine and serotonin while having a calming effect to ease anxious feelings.
  • The reishi mushroom (Ganoderma lucidum) was known as the "mushroom of immortality" in ancient China. This potent adaptogen is renowned for promoting relaxation and sleep. Its triterpene compounds exert anti-anxiety effects by modulating GABA and other neurotransmitters.
  • Lion's mane (Hericium erinaceus) is a fluffy mushroom that contains bioactive polysaccharides and metabolites that boost nerve growth factor (NGF) to support neurological health. By protecting nerve cells, lion’s mane mushrooms can help maintain calm cognitive function.
  • Chaga is a birch tree parasite. It is packed with soothing triterpenes, polysaccharides, and antioxidants. Its adaptogenic properties help normalize cortisol and neurological responses to stress.

Together or individually, these four medicinal mushrooms can help regulate key biological pathways and neurochemicals involved in anxiety disorders. Their unique adaptogenic benefits make them promising natural supplements for anxiety relief.

Do Cordyceps help with mood?

Cordyceps' adaptogenic properties may contribute to improved mood by helping the body manage stress more effectively. While research on Cordyceps' direct impact on mood is limited, some users have reported enhanced mood and reduced stress levels when taking cordyceps mushroom supplement. Its potential to modulate stress response could indirectly support better mood regulation.

How does Cordyceps make you feel?

Cordyceps' effects are different for all people. Some people report improved energy levels, reduced fatigue, and enhanced overall well-being after using cordyceps mushroom supplements. These effects are likely attributed to its adaptogenic properties, which aim to support the body's resilience to stressors. 

While Cordyceps may not provide an immediate sensation, consistent use may contribute to an overall sense of vitality.

What does Cordyceps do to the brain?

Research on Cordyceps' effects on the brain is still evolving. Some studies suggest that Cordyceps sinensis may have neuroprotective properties and could potentially benefit brain health. However, the exact mechanisms through which Cordyceps interacts with the brain are not fully understood. Its adaptogenic properties could indirectly influence brain function by helping the body manage stress and promoting overall well-being.

Who should avoid Cordyceps?

Individuals with certain health conditions, such as autoimmune disorders, should exercise caution when considering cordyceps supplements. Cordyceps' effects on the immune system and gut microbiota could potentially interact with autoimmune conditions. 

Additionally, cancer patients and those with bleeding disorders should consult a healthcare professional before using cordyceps, as it may influence blood sugar levels and blood clotting. 

As with any supplement, talk to your medical avdisor before incorporating cordyceps into your regimen.

Resources

(n.d.). Anxiety Disorders: Types, Causes, Symptoms & Treatments. Cleveland Clinic. https://my.clevelandclinic.org/health/diseases/9536-anxiety-disorders

Tuli, H. S., Sandhu, S. S., & Sharma, A. K. (2013, February 19).Pharmacological and therapeutic potential of Cordyceps with special reference to Cordycepin - 3 Biotech. SpringerLink. https://doi.org/10.1007/s13205-013-0121-9

The Antidepressive and Anxiolytic Effects of Formula Consisted of Poria cocos and Cordyceps militaris Waster Medium Extract in Unpredictable Chronic Mild Stress Animal Model. (2020, May 29). ScienceDirect. https://doi.org/10.1093/cdn/nzaa057_028

Liao, L. Y., He, Y. F., Li, L., Meng, H., Dong, Y. M., Yi, F., & Xiao, P. G. (2018, November 16).A preliminary review of studies on adaptogens: comparison of their bioactivity in TCM with that of ginseng-like herbs used worldwide. PubMed Central (PMC). https://doi.org/10.1186/s13020-018-0214-9

Song, J., Wang, Y., Teng, M., Cai, G., Xu, H., Guo, H., Liu, Y., Wang, D., & Teng, L. (2015, August 17).Studies on the Antifatigue Activities of Cordyceps militaris Fruit Body Extract in Mouse Model. PubMed Central (PMC). https://doi.org/10.1155/2015/174616

Antidepressant-like effects of cordycepin in a mice model of chronic unpredictable mild stress - PubMed. (2014, January 1). PubMed. https://doi.org/10.1155/2014/438506

Jędrejko, K., Kała, K., Sułkowska-Ziaja, K., Krakowska, A., Zięba, P., Marzec, K., Szewczyk, A., Sękara, A., Pytko-Polończyk, J., & Muszyńska, B. (2022, September 21).Cordyceps militaris Fruiting Bodies, Mycelium, and Supplements: Valuable Component of Daily Diet. MDPI. https://doi.org/10.3390/antiox11101861

Antidepressant-like effects of water extract of Cordyceps militaris (Linn.) Link by modulation of ROCK2/PTEN/Akt signaling in an unpredictable chronic mild stress-induced animal model. (2021, May 8). ScienceDirect. https://doi.org/10.1016/j.jep.2021.114194

Fuxe, K., Marcellino, D., Borroto‐Escuela, D. O., Guescini, M., Fernández‐Dueñas, V., Tanganelli, S., Rivera, A., Ciruela, F., & Agnati, L. F. (2010, March 16).Adenosine–Dopamine Interactions in the Pathophysiology and Treatment of CNS Disorders. PubMed Central (PMC). https://doi.org/10.1111/j.1755-5949.2009.00126.x

Neuroprotective effects of natural cordycepin on LPS-induced Parkinson’s disease through suppressing TLR4/NF-κB/NLRP3-mediated pyroptosis. (2020, November 16). ScienceDirect. https://doi.org/10.1016/j.jff.2020.104274

Anti-inflammatory effects of cordycepin: A review - PubMed. (2020, October 8). PubMed. https://doi.org/10.1002/ptr.6890

Smiderle, F. R., Baggio, C. H., Borato, D. G., Santana-Filho, A. P., Sassaki, G. L., Iacomini, M., & L. D. Van Griensven, L. J. (2014, October 17).Anti-Inflammatory Properties of the Medicinal Mushroom Cordyceps militaris Might Be Related to Its Linear (1→3)-β-D-Glucan. PubMed Central (PMC). https://doi.org/10.1371/journal.pone.0110266

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